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Isolating higher yielding and more stable rice genotypes in stress environments: fine-tuning a selectionmethod using production and resilience score indices

《农业科学与工程前沿(英文)》 doi: 10.15302/J-FASE-2023521

摘要:

● Score index methods readily discriminate genotypes adapted to a target environment.

关键词: Aerobic rice     breeding selection     drought resilience     production capacity index     resilience capacity index     stress score index     upland    

Prediction of the shear wave velocity

Amoroso SARA

《结构与土木工程前沿(英文)》 2014年 第8卷 第1期   页码 83-92 doi: 10.1007/s11709-013-0234-6

摘要: The paper examines the correlations to obtain rough estimates of the shear wave velocity from non-seismic dilatometer tests (DMT) and cone penetration tests (CPT). While the direct measurement of is obviously preferable, these correlations may turn out useful in various circumstances. The experimental results at six international research sites suggest that the DMT predictions of from the parameters (material index), (horizontal stress index), (constrained modulus) are more reliable and consistent than the CPT predictions from (cone resistance), presumably because of the availability, by DMT, of the stress history index .

关键词: horizontal stress index     shear wave velocity     flat dilatometer test     cone penetration test    

基于平衡记分卡的连锁经营企业绩效评价研究

曹杰,曹国,何建敏

《中国工程科学》 2008年 第10卷 第4期   页码 90-96

摘要:

以平衡记分卡(BSC)为基础,从BSC的财务、客户、内部经营过程以及学习与成长等方面,设计了连锁经营企业的绩效考核指标体系与模糊综合评判模型,克服了传统评价体系的不足,有利于从成长的角度全面评价连锁企业绩效。

关键词: 平衡记分卡     连锁经营     绩效评价     模糊综合评价    

Propensity score-matched study and meta-analysis of cumulative outcomes of day 2/3 versus day 5/6 embryo

null

《医学前沿(英文)》 2017年 第11卷 第4期   页码 563-569 doi: 10.1007/s11684-017-0535-6

摘要:

The superiority of the cumulative outcomes of day 5/6 embryo transfer to those of day 2/3 embryo transfer in infertile couples has been debated. This retrospective study included data collected from 1051 patients from July 2011 to June 2014. Multiple maternal baseline covariates were subjected to propensity score matching analysis, and each day 5/6 group woman was matched to one day 2/3 group woman. A systematic meta-analysis was conducted to validate the results. After matching was completed, 217 patients on the day 2/3 group were matched with those on the day 5/6 group, and no significant differences in the baseline characteristics were observed between the two groups. The cumulative pregnancy rate (57.14% vs. 53.46%, OR 1.16, 95% CI 0.79–1.70) and cumulative live birth rate (53.00% vs. 49.77%, OR 1.14, 95% CI 0.78–1.66) of day 5/6 embryo transfers were higher than those of day 2/3 embryo transfers, but this difference was not significant. The mean cycles per live birth and mean days per live birth in the day 5/6 group were significantly lower than those in the day 2/3 group. This study demonstrated that day 5/6 embryo transfer is a more cost-effective and time-efficient policy than day 2/3 embryo transfer to produce a live baby.

关键词: blastocyst     embryo transfer     cumulative pregnancy rate     cumulative live birth rate     IVF    

Clinical risk score for invasive fungal diseases in patients with hematological malignancies undergoing

Ling Wang, Ying Wang, Jiong Hu, Yuqian Sun, He Huang, Jing Chen, Jianyong Li, Jun Ma, Juan Li, Yingmin Liang, Jianmin Wang, Yan Li, Kang Yu, Jianda Hu, Jie Jin, Chun Wang, Depei Wu, Yang Xiao, Xiaojun Huang

《医学前沿(英文)》 2019年 第13卷 第3期   页码 365-377 doi: 10.1007/s11684-018-0641-0

摘要: Invasive fungal disease (IFD) is a major infectious complication in patients with hematological malignancies. In this study, we examined 4889 courses of chemotherapy in patients with hematological diseases to establish a training dataset ( =3500) by simple random sampling to develop a weighted risk score for proven or probable IFD through multivariate regression, which included the following variables: male patients, induction chemotherapy for newly diagnosed or relapsed disease, neutropenia, neutropenia longer than 10 days, hypoalbuminemia, central-venous catheter, and history of IFD. The patients were classified into three groups, which had low (0–10, ~1.2%), intermediate (11–15, 6.4%), and high risk (>15, 17.5%) of IFD. In the validation set ( =1389), the IFD incidences of the groups were ~1.4%, 5.0%, and 21.4%. In addition, we demonstrated that anti-fungal prophylaxis offered no benefits in low-risk patients, whereas benefits were documented in intermediate (2.1% vs. 6.6%, =0.007) and high-risk patients (8.4% vs. 23.3%, =0.007). To make the risk score applicable for clinical settings, a pre-chemo risk score that deleted all unpredictable factors before chemotherapy was established, and it confirmed that anti-fungal prophylaxis was beneficial in patients with intermediate and high risk of IFD. In conclusion, an objective, weighted risk score for IFD was developed, and it may be useful in guiding antifungal prophylaxis.

关键词: invasive fungal diseases     hematological malignancies     chemotherapy     risk score     prophylaxis    

Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breast

Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen

《医学前沿(英文)》 2021年 第15卷 第4期   页码 621-628 doi: 10.1007/s11684-020-0738-0

摘要: Multi-gene assays have emerged as crucial tools for risk stratification in early-stage breast cancer. This study aimed to evaluate the prognostic significance of the 21-gene recurrence score (RS) in Chinese patients with pN0-1, estrogen receptor-positive (ER ), human epidermal growth factor receptor 2-negative (HER2 ) breast cancer. Among 800 patients recruited between 2009 and 2016, the median RS was 24 (0–69), with 27.4%, 46.8%, and 25.9% patients classified into low-, intermediate-, and high-risk groups. Cox regression analysis demonstrated that the high-risk category was associated with significantly higher odds of invasive disease-free survival (IDFS) and distant disease-free survival (DDFS) events compared with the low-risk category (IDFS: HR= 2.450, 95% CI 1.017–5.902, = 0.046; DDFS: HR= 2.829, 95% CI 1.013–7.901, = 0.047). No significant association between RS category and overall survival (OS) was found (intermediate vs. low: HR= 1.244, 95% CI 0.292–5.297, = 0.768; high vs. low: HR= 2.933, 95% CI 0.759–11.327, = 0.119). RS, as a continuous variable, was a highly significant predictor for IDFS (HR= 1.028, 95% CI 1.010–1.047, = 0.002), DDFS (HR= 1.030, 95% CI 1.010–1.051, = 0.003), and OS (HR= 1.034, 95% CI 1.007–1.063, = 0.014). Our findings suggested that RS may predict IDFS in Chinese patients with ER /HER2 breast cancer with N0 or N1 disease.

关键词: early breast cancer     21-gene assay     recurrence score     prognosis    

Research on port ecological suitability evaluation index system and evaluation model

Yaofeng XIE,Xia LV,Ru LIU,Liuyan MAO,Xiaoxi LIU

《结构与土木工程前沿(英文)》 2015年 第9卷 第1期   页码 65-70 doi: 10.1007/s11709-014-0258-6

摘要: Along with the rapid development of port building, the negative impacts of port’s construction and operation on the coastline ecosystem are also increasingly strong. Therefore, it’s urgent to establish a scientific and complete system of port ecological suitability evaluation. This paper pointed out the characteristics of port ecological effects and the principles of selecting evaluation index, and used the “pressure-state-response (PSR)” model to analysis the various pressures on the environment caused by port construction and operation, and the system’s response. On this basis, we constructed the port ecological suitability evaluation index. This model used the combination of qualitative and quantitative analytic hierarchy process, to meet the multi-level, multi-objective characteristics of evaluation index system. The evaluation index system and evaluation model can be used to analysis the ecological suitability of port projects comprehensively and have some guiding significance to the port ecological suitability evaluation.

关键词: port     ecological suitability     press-state-response (PSR) model     evaluation index system    

A total torque index for dynamic performance evaluation of a radial symmetric six-legged robot

Kejia LI, Xilun DING, Marco CECCARELL

《机械工程前沿(英文)》 2012年 第7卷 第2期   页码 219-230 doi: 10.1007/s11465-012-0320-9

摘要:

This article focuses on the dynamic index and performance of a radial symmetric six-legged robot. At first the structure of the robot is described in brief and its inverse kinematics is presented. Then the dynamic model is formulated as based on the Lagrange equations. A novel index of total torque is proposed by considering the posture of the supporting legs. The new index can be used to optimize the leg’s structure and operation for consuming minimum power and avoiding unstable postures of the robot. A characterization of the proposed six-legged robot is obtained by a parametric analysis of robot performance through simulation using the presented dynamic model. Main influences are outlined as well as the usefulness of the proposed performance index.

关键词: six-legged robots     dynamic modeling     performance index    

skin and soft tissue infections after allogeneic hematopoietic stem cell transplantation: PAH risk score

《医学前沿(英文)》 2022年 第16卷 第6期   页码 957-968 doi: 10.1007/s11684-021-0910-1

摘要: Skin and soft tissue infections (SSTIs) refer to infections involving the skin, subcutaneous tissue, fascia, and muscle. In transplant populations with hematological malignancies, an immunocompromised status and the routine use of immunosuppressants increase the risk of SSTIs greatly. However, to date, the profiles and clinical outcomes of SSTIs in hematopoietic stem cell transplantation (HSCT) patients remain unclear. This study included 228 patients (3.67%) who developed SSTIs within 180 days after allogeneic HSCT from January 2004 to December 2019 in Peking University People’s Hospital. The overall annual survival rate was 71.5%. We compared the differences between survivors and non-survivors a year after transplant and found that primary platelet graft failure (PPGF), comorbidities of acute kidney injury (AKI), and hospital-acquired pneumonia (HAP) were independent risk factors for death in the study population. A PPGF–AKI–HAP risk stratification system was established with a mortality risk score of 1×PPGF+1×AKI+1×HAP. The areas under the curves of internal and external validation were 0.833 (95% CI 0.760–0.906) and 0.826 (95% CI 0.715–0.937), respectively. The calibration plot revealed the high consistency of the estimated risks, and decision curve analysis showed considerable net benefits for patients.

关键词: skin and soft tissue infections     hematopoietic stem cell transplantation     risk stratification system     mortality    

determination of tobramycin by reversed-phase ion-pair high performance liquid chromatography with a refractive index

Liang ZHU, Jingkang WANG

《化学科学与工程前沿(英文)》 2013年 第7卷 第3期   页码 322-328 doi: 10.1007/s11705-013-1348-z

摘要: A simple and direct method without a derivation step for routine analysis of tobramycin has been developed. This method used reversed-phase ion-pair high performance liquid chromatography (HPLC) with a refractive index (RI) detector and a C18 column which is stable at pH above 1.00. The presence of 4.50 mg·mL trifluoroacetic acid (TFA) in the mobile phase improved the protonation of tobramycin and the formation of ion-pairs, and thus reduced its hydrophility. This unique separation–detection combination showed good linearity with correlation coefficients 0.9996 in the concentration range of 0.25–2.50 mg·mL . The quantitation limit and detection limit were determined to be 0.23 mg·mL and 0.071 mg·mL , respectively. Tobramycin was recovered in 98.00%, 98.84% and 99.64% for tobramycin solutions at concentrations of 2.25 mg·mL , 1.50 mg·mL and 0.75 mg·mL , respectively. The relative standard deviations for six spiked samples ranged from 0.20% to 2.40%, indicating a good reproducibility of this method.

关键词: tobramycin     aminoglycoside     refractive index detector     high-performance liquid chromatography     ion-pairing    

EFFECTS OF TRANSPORT STRESS ON THE INTESTINES INVOLVING NEURONAL NITRIC OXIDE SYNTHASE

《农业科学与工程前沿(英文)》   页码 285-295 doi: 10.15302/J-FASE-2022469

摘要:

● Transport stress declined the level of leukocytes including lymphocytes in rat serum.

关键词: intestine     nNOS     nNOS-positive neurons     transport stress    

Analysis on annealing-induced stress of blind-via TSV using FEM

Jie SHAO, Tielin SHI, Li DU, Lei SU, Xiangning LU, Guanglan LIAO

《机械工程前沿(英文)》 2018年 第13卷 第3期   页码 401-410 doi: 10.1007/s11465-017-0457-7

摘要:

Copper-filled through silicon via (TSV) is a promising material owing to its application in high-density three-dimensional (3D) packaging. However, in TSV manufacturing, thermo-mechanical stress is induced during the annealing process, often causing reliability issues. In this paper, the finite element method is employed to investigate the impacts of via shape and SiO2 liner uniformity on the thermo-mechanical properties of copper-filled blind-via TSV after annealing. Top interface stress analysis on the TSV structure shows that the curvature of via openings releases stress concentration that leads to ~60 MPa decrease of normal stresses, sxx and syy, in copper and ~70 MPa decrease sxx of in silicon. Meanwhile, the vertical interface analysis shows that annealing-induced stress at the SiO2/Si interface depends heavily on SiO2 uniformity. By increasing the thickness of SiO2 linear, the stress at the vertical interface can be significantly reduced. Thus, process optimization to reduce the annealing-induced stress becomes feasible. The results of this study help us gain a better understanding of the thermo-mechanical behavior of the annealed TSV in 3D packaging.

关键词: through silicon via (TSV)     annealing-induced stress     interface stress     plastic deformation     finite element method    

SUSTAINABLE NITROGEN MANAGEMENT INDEX: DEFINITION, GLOBAL ASSESSMENT AND POTENTIAL IMPROVEMENTS

《农业科学与工程前沿(英文)》 2022年 第9卷 第3期   页码 356-365 doi: 10.15302/J-FASE-2022458

摘要:

● A composite N management index is proposed to measure agriculture sustainability.

关键词: global assessment     indicator     nitrogen management     sustainable agriculture     sustainable development goals    

An investigation on stress distribution effect on multi- piezoelectric energy harvesters

Hailu YANG, Dongwei CAO

《结构与土木工程前沿(英文)》 2017年 第11卷 第3期   页码 301-307 doi: 10.1007/s11709-017-0404-z

摘要: With the fast development of piezoelectric materials and due to its green and renewable characteristics, the piezoelectric energy harvesting technology has been paid more and more attention by pavement engineers. The stress distribution will significantly affect the piezoelectric material performance. In this paper, the effects of multiple piezoelectric elements on the generation of electrical energy and output power are studied. In the case of constant external load, the number of the piezoelectric units does not necessarily produce more energy. When the same multi piezoelectric units work together, if the stress state of the piezoelectric units is different, the total output energy affected by the connection mode. For uneven stress distribution, the optimal output mode is that each of the piezoelectric units rectified before connected in parallel.

关键词: piezoelectric transducer     uneven stress     impedance matching     optimal energy output    

The formation mechanism and the influence factor of residual stress in machining

null

《机械工程前沿(英文)》 2014年 第9卷 第3期   页码 265-269 doi: 10.1007/s11465-014-0311-0

摘要:

Residual stresses generated in cutting process have important influences on workpiece performance. The paper presents a method of theoretical analysis in order to explicate the formation mechanism of residual stresses in cutting. An important conclusion is drawn that the accumulated plastic strain is the main factor which determines the nature and the magnitude of surface residual stresses in the workpiece. On the basis of the analytical model for residual stress, a series of simulations for residual stress prediction during cutting AISI 1045 steel are implemented in order to obtain the influences of cutting speed, depth of cut and tool edge radius on surface residual stress in the workpiece. And these influences are explained from the perspective of formation mechanism of residual stress in cutting. The conclusions have good applicability and can be used to guide the parameters selection in actual production.

关键词: residual stress     analytical model     strain     plastic     cutting parameter    

标题 作者 时间 类型 操作

Isolating higher yielding and more stable rice genotypes in stress environments: fine-tuning a selectionmethod using production and resilience score indices

期刊论文

Prediction of the shear wave velocity

Amoroso SARA

期刊论文

基于平衡记分卡的连锁经营企业绩效评价研究

曹杰,曹国,何建敏

期刊论文

Propensity score-matched study and meta-analysis of cumulative outcomes of day 2/3 versus day 5/6 embryo

null

期刊论文

Clinical risk score for invasive fungal diseases in patients with hematological malignancies undergoing

Ling Wang, Ying Wang, Jiong Hu, Yuqian Sun, He Huang, Jing Chen, Jianyong Li, Jun Ma, Juan Li, Yingmin Liang, Jianmin Wang, Yan Li, Kang Yu, Jianda Hu, Jie Jin, Chun Wang, Depei Wu, Yang Xiao, Xiaojun Huang

期刊论文

Prognostic value of the 21-gene recurrence score in ER-positive, HER2-negative, node-positive breast

Jiayi Wu, Weiqi Gao, Xiaosong Chen, Chunxiao Fei, Lin Lin, Weiguo Chen, Ou Huang, Siji Zhu, Jianrong He, Yafen Li, Li Zhu, Kunwei Shen

期刊论文

Research on port ecological suitability evaluation index system and evaluation model

Yaofeng XIE,Xia LV,Ru LIU,Liuyan MAO,Xiaoxi LIU

期刊论文

A total torque index for dynamic performance evaluation of a radial symmetric six-legged robot

Kejia LI, Xilun DING, Marco CECCARELL

期刊论文

skin and soft tissue infections after allogeneic hematopoietic stem cell transplantation: PAH risk score

期刊论文

determination of tobramycin by reversed-phase ion-pair high performance liquid chromatography with a refractive index

Liang ZHU, Jingkang WANG

期刊论文

EFFECTS OF TRANSPORT STRESS ON THE INTESTINES INVOLVING NEURONAL NITRIC OXIDE SYNTHASE

期刊论文

Analysis on annealing-induced stress of blind-via TSV using FEM

Jie SHAO, Tielin SHI, Li DU, Lei SU, Xiangning LU, Guanglan LIAO

期刊论文

SUSTAINABLE NITROGEN MANAGEMENT INDEX: DEFINITION, GLOBAL ASSESSMENT AND POTENTIAL IMPROVEMENTS

期刊论文

An investigation on stress distribution effect on multi- piezoelectric energy harvesters

Hailu YANG, Dongwei CAO

期刊论文

The formation mechanism and the influence factor of residual stress in machining

null

期刊论文